Diarrhoeal disease and subsequent risk of death in infants and children residing in low-income and middle-income countries: analysis of the GEMS case-control study and 12-month GEMS-1A follow-on study

Dec 23, 2019

Published Research

A follow-on analysis of the Global Enteric Multicenter Study (GEMS), published in The Lancet Global Health, finds that the risk of death is increased following moderate-to-severe diarrhea and, to a lesser extent, less-severe diarrhea. Considering the higher volume of LSD cases than MSD, more deaths are expected among children with LSD than in those with MSD. Because the major attributable LSD-associated and MSD-associated pathogens are the same, these findings support the implementation of vaccines and rapid diagnosis and treatment interventions against these major pathogens.


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